Nicotiana benthamiana plants expressing the Ruby construct (encodes enzymes of betalain biosynthesis).
Projects will be focused on addressing major global challenges aligned with the UK’s National Engineering Biology Programme:
Clean growth (e.g. photosynthetic biomanufacturing of proteins and natural products)
Resilient food systems (e.g. engineering of agricultural traits such as defence and photosynthesis)
Environmental sustainability (e.g. phytoremediation of rare earth metals)
Technologies for engineering plants (e.g. development of new tools for gene editing/ large-scale screening/ synthetic control).
The projects advertised in 2026 were:
Re-engineering photoprotection by concerted optimization of sensor and quencher
Programming green algae for the production of omega-3 fatty acids and wax
Engineering plant rubisco enzymes through high-throughput enzyme assays and cryo-EM
Engineering Plant Cell Size and Material Properties using Fungal Proteins
High-throughput screening of Rubisco variants to enhance plant productivity
Optimisation of nanocomplexes for the delivery of RNA to plants
Engineering plant immune responses
Year-Round Beet: engineering a controllable flowering switch for reliable seed production with zero bolting in commercial fields
SynProm: Fast, modular spatio-temporal transcriptional reporters for plants
Designer lettuce: re-wiring defence networks to engineer disease resistance
AI-Guided Design of RNA-structure-based Antiviral Systems for treating plant virus in sugar beets
A toolkit to engineer root-soil interactions
Developing genetic circuits to control and tune gene expression in mesophyll cells for programmable traits for sustainable agriculture
Developing New Strategies for Rapid Elucidation of Bioactive Pathways from Plant Biosynthetic Gene Clusters
Redesigning the Meiotic Map: Chromosome Engineering as a Tool to Control Genetic Recombination
Collaborative projects (CASE)
We fund a number of projects that are collaborative with industry partners addressing industry needs. These are known as CASE projects.
CASE projects will be prioritised during recruitment. The financial and in-kind contributions required from industry partners vary depending on the size of the company and the host university.
Please get in touch through plant-biodesign-network@york.ac.uk if you are interested in finding out more.